Humber Admissions Practice Test

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What is the primary function of the smooth endoplasmic reticulum (ER)?

Lipid synthesis
Protein synthesis
DNA replication
Cell division

The correct answer is: Lipid synthesis

The smooth endoplasmic reticulum (ER) primarily functions in lipid synthesis, which includes the production of phospholipids, cholesterol, and steroid hormones. This organelle is particularly abundant in cells that are involved in the metabolism of fats, such as liver and adrenal cells. The smooth ER also plays a role in detoxifying certain chemicals and storing calcium ions, which are important for various cellular processes. Unlike the rough ER, which is studded with ribosomes and primarily responsible for protein synthesis, the smooth ER lacks these ribosomes and is specialized for different functions that are essential for maintaining cellular health and metabolism. Therefore, its role in lipid synthesis is crucial for maintaining cell membrane integrity and producing vital lipid-based molecules necessary for various biochemical processes within the organism.